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Oxidative stress

Intervention

3 papers2 findings

MeSH

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Labs are independent when their papers share no last author and no institution.

  • 2 independent labs in 1 country
  • 1 trial
  • Funders: National Institute of Environmental Health Sciences and others
  • Model organisms2

Outcomes

2

mitochondrial remodeling

upin yeast cells1

1 study

  1. Oxidative stress induces mitochondrial remodeling in yeast cells.

    “mitochondria exhibit similar sphingolipid-dependent morphological transitions following acute exposure to oxidative stress.”

    Cellsacute exposure

    Sphingolipid metabolism drives mitochondria remodeling during aging and oxidative stress

    bioRxiv : the preprint server for biology27 Feb 2025Preprint

Ubiquitin–proteasome system

upin flies1

1 study

  1. Oxidative stress increases ubiquitin–proteasome system in flies.

    “upregulating protective systems, such as their proteasomal proteolytic capacity to remove oxidized proteins”

    Model organismschronic or repeated stress

    Oxidative stress adaptation with acute, chronic, and repeated stress

    Free radical biology & medicine9 Nov 2012

More on Ubiquitin–proteasome system

Trial sponsors

Funding

52 grants since 2016

Japan Society for the Promotion of ScienceJP¥166.1mFundacao de Amparo a Pesquisa do Estado de Sao PauloHealth and Medical Research FundHK$2.5m

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