Osteopontin
- 2 independent labs in 2 countries
- Funders: Australian Research Council and 8 more
- Animals1
- Cells1
Outcomes
4Hair growth
upin human cells1upin mice1
1 study
Hair growth
upin human cells1upin mice1
Osteopontin induces hair growth in human cells.
“it stimulates new growth of human hair follicles”
Cells
Signalling by senescent melanocytes hyperactivates hair growth
NatureJun 21, 2023
Osteopontin induces hair growth in mice.
“Injection of osteopontin or its genetic overexpression is sufficient to induce robust hair growth in mice”
Animals
Signalling by senescent melanocytes hyperactivates hair growth
NatureJun 21, 2023
Trophic effects on human osteoblasts
upin human cells1
1 study
Trophic effects on human osteoblasts
upin human cells1
Osteopontin improves trophic effects on human osteoblasts in human cells.
“The conditioned medium from P10 ASCs on OPN-coating improved trophic effects on HOBs.”
Cellsconditioned medium from P10 ASCs on OPN-coating
Stem cell reviews and reportsMar 12, 2024
Stem cell differentiation
upin human cells1
1 study
Stem cell differentiation
upin human cells1
Osteopontin increases stem cell differentiation in human cells.
“P10 ASCs on OPN-coated surface showed rejuvenated phenotype and enhanced osteogenic differentiation.”
CellsP10 senescent ASCsOPN-coated surfaceadipose-derived mesenchymal stem cells
Stem cell reviews and reportsMar 12, 2024
Cellular senescence
downin human cells1
1 study
Cellular senescence
downin human cells1
Osteopontin decreases cellular senescence in human cells.
“P10 ASCs on OPN-coated surface showed rejuvenated phenotype and enhanced osteogenic differentiation.”
CellsP10 senescent ASCsOPN-coated surfaceadipose-derived mesenchymal stem cells
Stem cell reviews and reportsMar 12, 2024
Funding
2 grants since 2020National Eye InstituteUS$1.8mJapan Society for the Promotion of ScienceJP¥4.3m