NLRP3 inhibitors

NLRP3 inhibitors decrease bone marrow stem cell dysfunction in mice.

“The deleterious effects of PM2.5 on MSCs and HSCs in T2DM were reversed by an NLR family pyrin domain-containing 3 (NLRP3) inhibitor”

AnimalsPM2.5-exposed type 2 diabetes mellitus micebone marrow mesenchymal and hematopoietic stem cells

Fine particulate matter accelerates the senescence of bone marrow-conserved stem cells in a type 2 diabetes mellitus mouse model

Journal of hazardous materials·27 Jun 2026