Mesenchymal stem cell exosomes

3 papers3 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Labs are independent when their papers share no last author and no institution.

Against: findings that point the other way from most findings on the same outcome.

On aging: the drug’s trials ARN judged to be about aging, of every trial that tests it for any use.

No results posted: trials that ended more than a year ago with no results on ClinicalTrials.gov and no paper in ARN’s record.

Company ties: findings with an author at a company, or from a paper whose competing-interests statement declares ties to one.

1 lab in 1 country

Funders: China Postdoctoral Science Foundation and 1 more

Animals1

Outcomes

3

Osteoarthritis

downin animals1

1 study

Mesenchymal stem cell exosomes decrease osteoarthritis.
“Both in vitro and in vivo experiments demonstrated that iExos exhibit superior antisenescent activity in chondrocytes and more effectively attenuate OA progression.”
Animals
Interferon-γ-Induced Mesenchymal Stem Cell Exosomes Attenuate Chondrocyte Senescence and Osteoarthritis Progression by Hsp70
ACS nano27 Nov 2025

More on Osteoarthritis

Cellular senescence

downin cells1

1 study

Mesenchymal stem cell exosomes decrease cellular senescence in cells.
“iExos exhibit superior antisenescent activity in chondrocytes and more effectively attenuate OA progression.”
Cells
Interferon-γ-Induced Mesenchymal Stem Cell Exosomes Attenuate Chondrocyte Senescence and Osteoarthritis Progression by Hsp70
ACS nano27 Nov 2025

More on Cellular senescence

Age-related diseases

downin reviews1

1 study

Mesenchymal stem cell exosomes decrease age-related diseases.
“MSC-Exos, which contain a diverse array of proteins, miRNAs, and other biomolecules, can deliver MSC-derived bioinformatics to target cells and demonstrate comparable therapeutic benefits to MSCs”
Review
Advances in mesenchymal stem cell and exosome-based therapies for aging and age-related diseases
Stem cell research & therapy26 Jul 2025

More on Age-related diseases

Latest

1 in 12 months

ACS Nano28 Nov

Interferon-γ-Induced Mesenchymal Stem Cell Exosomes Attenuate Chondrocyte Senescence and Osteoarthritis Progression by Hsp70

Experiments in animalsOsteoarthritis

Aging and Disease3 Sep

Crossing Pathological Boundaries: Multi-Target Restoration of the Neurovascular Unit in Alzheimer's and Vascular Dementia-From Modern Therapeutics to Traditional Chinese Medicine

ReviewVascular dementia

Stem Cell Research & Therapy26 Jul

Advances in mesenchymal stem cell and exosome-based therapies for aging and age-related diseases

ReviewMesenchymal stem cells