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Lipid enals

Intervention

1 paper2 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country
  • Funders: American Heart Association and 3 more
  • Animals1

Outcomes

1

Cellular senescence

upin human cells1upin mouse cells1

1 study

  1. Lipid enals induce cellular senescence in mouse cells.

    “4-hydroxynonenal (4-HNE), 4-hydroxyhexenal (4-HHE) or 4-oxo-2-nonenal (4-ONE) initiate the cellular senescence program of IMR90 fibroblasts and murine adipose stem cells.”

    Cellsadipose stem cell

    Lipid peroxidation products induce carbonyl stress, mitochondrial dysfunction, and cellular senescence in human and murine cells

    Aging cell11 Oct 2024

  2. Lipid enals induce cellular senescence in human cells.

    “4-hydroxynonenal (4-HNE), 4-hydroxyhexenal (4-HHE) or 4-oxo-2-nonenal (4-ONE) initiate the cellular senescence program of IMR90 fibroblasts and murine adipose stem cells.”

    CellsIMR90 fibroblast

    Lipid peroxidation products induce carbonyl stress, mitochondrial dysfunction, and cellular senescence in human and murine cells

    Aging cell11 Oct 2024

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