Lifestyle modification

Intervention2 papers2 findings

  • Human trial1

Outcomes

2

HbA1c

downin humans1−0.4%Moderate certainty

1 study
  1. Lifestyle modification decreases HbA1c in humans (-0.4%).

    “and HbA1c (-0.4%; all p”

    Human trialprediabetes6 monthsn = 181

    Lifestyle modification reduces phenotypic age in adults with prediabetes · Frontiers in aging · 10 Sep 2026

HbA1c →

PhenoAge

downin humans1Moderate certainty

1 study
  1. Lifestyle modification decreases PhenoAge in humans (-4.9 vs. +1.3 years).

    “participants in the lifestyle modification program (LMP) showed a significant reduction in PhenoAge (-4.9 vs. +1.3 years; between-group p”

    Human trialprediabetes6 monthsn = 181

    Lifestyle modification reduces phenotypic age in adults with prediabetes · Frontiers in aging · 10 Sep 2026

PhenoAge →

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Frontiers in AgingHuman trial

Lifestyle modification reduces phenotypic age in adults with prediabetes

A six-month randomized trial in Arab adults found structured diet and exercise reduced biological age alongside metabolic markers.A six-month randomized trial in Arab adults found structured diet and exercise reduced biological age alongside metabolic markers.