Lactobacillus paracasei
Lactobacillus paracasei has been studied in 6 papers since 2019: none in people yet, 4 in animals, 1 review; 3 in the past year. The research so far is in animals.
6 papers study it9 findingsUpdated
- 3 independent labs in 2 countries
- Funders: National Institute on Aging and others
- Animals4
What did studies of Lactobacillus paracasei find?
7Studies of Lactobacillus paracasei measured 7 outcomes; the most studied are cognitive function (2 studies), physical function (2) and butyric acid (1).
Cognitive function
upin mice1upin rats1
2 studies
Cognitive function
upin mice1upin rats1
Lactobacillus paracasei improves cognitive function in rats.
“prevention of both physical and cognitive decline especially in female rats”
Animalsaged ratsfemales
The journals of gerontology. Series A, Biological sciences and medical sciences
Lactobacillus paracasei improves cognitive function in mice.
“improves physical and cognitive functions.”
Animals
GeroScience
Physical function
upin mice1upin rats1
2 studies
Physical function
upin mice1upin rats1
Lactobacillus paracasei improves physical function in rats.
“we suggest the efficacy of this Ang(1-7) releasing Lactobacillus paracasei (LPA) as either an alternative strategy to exercise, or more likely as an adjuvant to moderate exercise, for the prevention of both physical and cognitive decline especially in female rats”
Animalsaged ratsfemales
The journals of gerontology. Series A, Biological sciences and medical sciences
Lactobacillus paracasei improves physical function in mice.
“improves physical and cognitive functions.”
Animals
GeroScience
Butyric acid
upin mice1
1 study
Butyric acid
upin mice1
Lactobacillus paracasei increases butyric acid in mice.
“plasma concentrations of butyric acid significantly elevated in aged mice after L9 intervention.”
Animalsgavage4 × 1010 CFU in 100 μL9 monthsmalesn = 4
Nutrients
SLC7A8
upin mice1
1 study
SLC7A8
upin mice1
Lactobacillus paracasei increases SLC7A8 in mice.
“both plasma amino acid levels and the expression of large neutral amino acid transporter 2 (LAT2), a key transporter associated with neutral amino acid absorption, were significantly increased.”
Animalsgavage4 × 1010 CFU in 100 μL9 monthsmalesn = 4
Nutrients
Amino acids
upin mice1
1 study
Amino acids
upin mice1
Lactobacillus paracasei increases amino acids in mice.
“both plasma amino acid levels and the expression of large neutral amino acid transporter 2 (LAT2), a key transporter associated with neutral amino acid absorption, were significantly increased.”
Animalsgavage4 × 1010 CFU in 100 μL9 monthsmalesn = 4
Nutrients
Inflammation
downin mice1
1 study
Inflammation
downin mice1
Lactobacillus paracasei decreases inflammation in mice.
“feeding of heat-killed D3-5 to old mice (> 79 weeks) prevents high- fat diet-induced metabolic dysfunctions, decreases leaky gut and inflammation, and improves physical and cognitive functions.”
Animalshigh-fat diet-induced metabolic dysfunctions
GeroScience
Lifespan
upin worms1
1 study
Lifespan
upin worms1
Lactobacillus paracasei extends lifespan in worms.
“Lactobacillus paracasei D3-5 strain (D3-5), even in the non-viable form, extends life span of Caenorhabditis elegans.”
Model organismsnon-viable form
GeroScience