Angiotensin

1. Angiotensin inhibits NF-κB signalling in mice.

   “inhibiting NF-κB activation, critical for inflammation suppression.”

   Animalsin elastase-induced emphysemaencapsulated in hydroxypropyl-β-cyclodextrinlung4 weeksmales

   Oral Angiotensin-(1-7) formulation after established elastase-induced emphysema suppresses inflammation and restores lung architecture

   Frontiers in pharmacology·18 Jun 2025

More on NF-κB signalling

1. Angiotensin activates wnt/β-catenin signalling in mice.

   “reactivating the Wnt/β-catenin pathway for tissue regeneration”

   Animalsin elastase-induced emphysemaencapsulated in hydroxypropyl-β-cyclodextrinlung4 weeksmales

   Oral Angiotensin-(1-7) formulation after established elastase-induced emphysema suppresses inflammation and restores lung architecture

   Frontiers in pharmacology·18 Jun 2025

More on Wnt/β-catenin signalling

1. Angiotensin inhibits cellular senescence in mice.

   “suppressing inflammation and senescence.”

   Animalsin elastase-induced emphysemaencapsulated in hydroxypropyl-β-cyclodextrinlung4 weeksmales

   Oral Angiotensin-(1-7) formulation after established elastase-induced emphysema suppresses inflammation and restores lung architecture

   Frontiers in pharmacology·18 Jun 2025

More on Cellular senescence

1. Angiotensin inhibits inflammation in mice.

   “suppressing inflammation and senescence.”

   Animalsin elastase-induced emphysemaencapsulated in hydroxypropyl-β-cyclodextrinlung4 weeksmales

   Oral Angiotensin-(1-7) formulation after established elastase-induced emphysema suppresses inflammation and restores lung architecture

   Frontiers in pharmacology·18 Jun 2025

More on Inflammation

1. Angiotensin decreases lung tissue damage in mice.

   “treatment with Ang-(1-7) reversed these changes, reducing collagen deposition, restoring alveolar structure, and suppressing inflammation and senescence.”

   Animalsin elastase-induced emphysemaencapsulated in hydroxypropyl-β-cyclodextrinlung4 weeksmales

   Oral Angiotensin-(1-7) formulation after established elastase-induced emphysema suppresses inflammation and restores lung architecture

   Frontiers in pharmacology·18 Jun 2025

1. Angiotensin decreases gut microbial dysbiosis in mice.

   “Gut microbial dysbiosis in aging was evident by decreased richness and altered beta diversity that were reversed by Ang-(1-7)”

   Animalsgutmales

   Restoration of the gut barrier integrity and restructuring of the gut microbiome in aging by angiotensin-(1-7)

   Clinical science (London, England : 1979)·31 May 2023

1. Angiotensin decreases inflammatory cell infiltration in mice.

   “Infiltration of CD11b+ or F4/80+ inflammatory cells in the old colons were decreased by Ang-(1-7).”

   Animalscolonmales

   Restoration of the gut barrier integrity and restructuring of the gut microbiome in aging by angiotensin-(1-7)

   Clinical science (London, England : 1979)·31 May 2023

1. Angiotensin increases Cldn1 expression in mice.

   “Expression of claudin 1 and occludin in the aging colon was increased by Ang-(1-7).”

   Animalscolonmales

   Restoration of the gut barrier integrity and restructuring of the gut microbiome in aging by angiotensin-(1-7)

   Clinical science (London, England : 1979)·31 May 2023

More on Cldn1 expression

1. Angiotensin increases intestinal stem cell number in mice.

   “Epithelial disintegrity, reduced number of goblet cells and ISCs in the old group were restored by Ang-(1-7).”

   Animalscolonmales

   Restoration of the gut barrier integrity and restructuring of the gut microbiome in aging by angiotensin-(1-7)

   Clinical science (London, England : 1979)·31 May 2023

More on Intestinal stem cell number

1. Angiotensin decreases intestinal permeability in mice.

   “Increased intestinal permeability and plasma levels of zonulin-1 in the Old group were normalized by Ang-(1-7).”

   Animalscolonmales

   Restoration of the gut barrier integrity and restructuring of the gut microbiome in aging by angiotensin-(1-7)

   Clinical science (London, England : 1979)·31 May 2023