Klotho-enriched extracellular vesicles
Intervention1 paper2 findings
- Cells1
Outcomes
2Stem cell differentiation
upin human cells1
1 study
Stem cell differentiation
upin human cells1
Klotho-enriched extracellular vesicles increase stem cell differentiation in human cells.
“KL-EVs rescued the age-related differentiation bias of adult BMSCs by robustly prompting their osteogenic differentiation capacity.”
Cellsin vitro
Characterization of Umbilical Cord Mesenchymal Stromal Cells Overexpressing Klotho and In Vitro Anti-Aging Efficacy of Their Derived Extracellular Vesicles · International journal of molecular sciences · 19 Sep 2026
Cellular senescence
downin human cells1
1 study
Cellular senescence
downin human cells1
Klotho-enriched extracellular vesicles decrease cellular senescence in human cells.
“KL-EVs profoundly rescued multifaceted senescent phenotypes in both adult bone marrow mesenchymal stem cells (BMSCs) and human renal tubular epithelial cells (HK-2) in vitro.”
Cellsin vitro
Characterization of Umbilical Cord Mesenchymal Stromal Cells Overexpressing Klotho and In Vitro Anti-Aging Efficacy of Their Derived Extracellular Vesicles · International journal of molecular sciences · 19 Sep 2026
Latest
1International Journal of Molecular SciencesCells