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High-intensity training

Intervention

1 paper4 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Labs are independent when their papers share no last author and no institution.

Against: findings that point the other way from most findings on the same outcome.

On aging: the drug’s trials ARN judged to be about aging, of every trial that tests it for any use.

No results posted: trials that ended more than a year ago with no results on ClinicalTrials.gov and no paper in ARN’s record.

Company ties: findings with an author at a company, or from a paper whose competing-interests statement declares ties to one.

  • 1 lab in 1 country
  • Funders: ADA Foundation and 3 more
  • Human trial1

Outcomes

4

HDL cholesterol

downin humans1−15% compared with control

1 study

  1. High-intensity training decreases HDL cholesterol in humans (-15% compared with control).

    “At follow-up, HDL (high-density lipoprotein)-cholesterol (-15 %, p < .01) and glucose (26 %, p < .01) decreased/increased(respectively) more in the TG than CG.”

    Human trialoutpatients with schizophrenia; compared with control group5-year follow-up

    The long-lasting impact of high-intensity training via collaborative care in patients with schizophrenia: A 5-year follow-up study

    Schizophrenia research27 Dec 2024

More on HDL cholesterol

Muscle power

upin humans1+26% compared with control

1 study

  1. High-intensity training increases muscle power in humans (+26% compared with control).

    “The TG increased V̇O2peak (11 %, p < .01), scaled 1RM (40 %, p < .001), and power (26 %, p < .001)”

    Human trialoutpatients with schizophrenia; compared with control groupaerobic interval and leg press maximal strength training with transportation and training supervision2 sessions per week1 yearn = 48

    The long-lasting impact of high-intensity training via collaborative care in patients with schizophrenia: A 5-year follow-up study

    Schizophrenia research27 Dec 2024

Scaled one-repetition maximum

upin humans1+40% compared with control

1 study

  1. High-intensity training increases scaled one-repetition maximum in humans (+40% compared with control).

    “The TG increased V̇O2peak (11 %, p < .01), scaled 1RM (40 %, p < .001), and power (26 %, p < .001)”

    Human trialoutpatients with schizophrenia; compared with control groupaerobic interval and leg press maximal strength training with transportation and training supervision2 sessions per week1 yearn = 48

    The long-lasting impact of high-intensity training via collaborative care in patients with schizophrenia: A 5-year follow-up study

    Schizophrenia research27 Dec 2024

Peak oxygen uptake

upin humans1+11% compared with control

1 study

  1. High-intensity training increases peak oxygen uptake in humans (+11% compared with control).

    “The TG increased V̇O2peak (11 %, p < .01), scaled 1RM (40 %, p < .001), and power (26 %, p < .001)”

    Human trialoutpatients with schizophrenia; compared with control groupaerobic interval and leg press maximal strength training with transportation and training supervision2 sessions per week1 yearn = 48

    The long-lasting impact of high-intensity training via collaborative care in patients with schizophrenia: A 5-year follow-up study

    Schizophrenia research27 Dec 2024

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