Football training

Football training has been studied in 7 papers since 2016: 2 trials and 5 observational studies in people. The newest paper, Sep 9, 2025: “Recreational football training preserves bone health in women over 9 years during the menopause transition”.

Intervention

7 papers study it19 findingsUpdated

See all 7 papers on football training

At a glance

Independent labs found the same change in people. 3 independent labs in 5 countries.

“Leg bone mineral content (BMC) increased in EXE (time × group, P = 0.005) resulting in a 56 g [4;108] higher (P = 0.04) total leg BMC in EXE compared to CON.”
Recreational football training preserves bone health in women over 9 years during the menopause transitionBiology of sport2025doi:10.5114/biolsport.2026.154145

1 of its findings points the other way.

Humans: replicated by independent labs. Cells, worms or flies and mice: nothing yet.
  • 3 independent labs in 5 countries
  • 1 finding against
  • Funders: Syddansk Universitet and others
  • 5 of 19 findings with company ties
  • Human trial2
  • Humans5

Studies in people

2 studies gave football training to people and measured what changed.

What changedDesignPeopleSource

up: Increases bone mineral content56 g [4;108] higher

up: Increases lean body mass+1.5 kg [1.0;2.1]

up: Improves sprint performancemaintained in EXE vs declined by 10% in CON

Randomized trial9 years25 peopleWomen45 ± 4 yrsMidlife adults; Postmenopausal womenBiology of sport, Sep 9, 2025

up: Improves chair rising performance+32% chair-rising performance, −24% stair-ascent time

up: Increases rate of force development+89% RFD, +18% hamstring strength

Randomized trial12 months9 peopleMen68.2 ± 3.2 yearsOlder adultsEuropean journal of applied physiology, Apr 11, 2016

What did studies of football training find?

16

Studies of football training measured 16 outcomes, among them telomere length, PINP and sprint performance.

Telomere length

upin humans2no changein humans1

2 studies
  1. Football training is linked with higher telomere length in lymphocytes and MNCs compared to YC (22-24% longer).

    “YF had 22-24% longer telomeres in lymphocytes and MNCs compared to YC.”

    Humansin lymphocytes and MNCs compared to YCmononuclear cellsfemales

    Football and team handball training postpone cellular aging in women

    Scientific reports

  2. Football training was not clearly linked with telomere length in humans (young football players vs young inactive controls).

    “but there was no significant between-group difference in telomere length”

    Humansyoung football players vs young inactive controlsmononuclear cellsmales

    Reduced telomere shortening in lifelong trained male football players compared to age-matched inactive controls

    Progress in cardiovascular diseases

  3. Football training is linked with higher telomere length in humans (elderly football players vs age-matched inactive controls) (+2.5% granulocyte, +1.3% lymphocyte telomere length).

    “EF showed 2.5% higher (p = 0.047) granulocyte telomere length and 1.3% higher (p = 0.009) lymphocyte telomere length compared to EC.”

    Humanselderly football players vs age-matched inactive controlsgranulocytes and lymphocyteslifelongmales

    Reduced telomere shortening in lifelong trained male football players compared to age-matched inactive controls

    Progress in cardiovascular diseases

More on Telomere length

PINP

upin humans1

1 study
  1. Football training increases PINP in humans (PINP +64% [29-100], CTX-I +95% [43;147]).

    “Plasma CTX-I and PINP increased (both P = 0.001) by 95% [43;147] and 64% [29-100] following EXE only (time × group, P = 0.003 and 0.02).”

    Human trial9 yearsfemalesn = 25

    Recreational football training preserves bone health in women over 9 years during the menopause transition

    Biology of sport

More on PINP

Sprint performance

upin humans1

1 study
  1. Football training improves sprint performance in humans (maintained in EXE vs declined by 10% in CON).

    “Finally, sprint performance was maintained in EXE but declined (P < 0.001) by 10% [5;14] in CON (time × group, P = 0.002).”

    Human trial9 yearsfemalesn = 25

    Recreational football training preserves bone health in women over 9 years during the menopause transition

    Biology of sport

Lean body mass

upin humans1

1 study
  1. Football training increases lean body mass in humans (+1.5 kg [1.0;2.1]).

    “Leg lean mass increased (P < 0.001) by 1.5 kg [1.0;2.1] in EXE (time × group, P = 0.006).”

    Human trialleg9 yearsfemalesn = 25

    Recreational football training preserves bone health in women over 9 years during the menopause transition

    Biology of sport

Bone mineral content

upin humans1

1 study
  1. Football training increases bone mineral content in humans (56 g [4;108] higher).

    “Leg bone mineral content (BMC) increased in EXE (time × group, P = 0.005) resulting in a 56 g [4;108] higher (P = 0.04) total leg BMC in EXE compared to CON.”

    Human trialleg9 yearsfemalesn = 25

    Recreational football training preserves bone health in women over 9 years during the menopause transition

    Biology of sport

MIR1303

downin humans1

1 study
  1. Football training is linked with lower MIR1303 in humans.

    “Football training down-regulates miR-1303 expression in muscle from VPG compared to CG”

    Humansskeletal muscle

    Regular football training down-regulates miR-1303 muscle expression in veterans

    European journal of applied physiology

More on MIR1303

Mitochondrial DNA copy number

upin humans1

1 study
  1. Football training is linked with higher mitochondrial DNA copy number in lymphocytes and MNCs compared to YC (19-20% higher).

    “YF showed 19-20% higher mtDNA copy number in lymphocytes and MNCs compared to YC.”

    Humansin lymphocytes and MNCs compared to YCmononuclear cellsfemales

    Football and team handball training postpone cellular aging in women

    Scientific reports

More on Mitochondrial DNA copy number

TRF2, Ku70 and POT1a mRNA expression

upin humans1

1 study
  1. Football training is linked with higher TRF2, Ku70 and POT1a mRNA expression in humans (young football players vs young inactive controls) (3.2-fold TRF2, 2.3-fold Ku70, 2.2-fold POT1a).

    “telomere repeat binding factor (TRF) 2 mRNA expression (3.2-fold, p = 0.003), Ku70 mRNA expression (2.3-fold, p < 0.001) and POT1a mRNA expression (2.2-fold, p = 0.002) compared to YC”

    Humansyoung football players vs young inactive controlsmononuclear cellsmales

    Reduced telomere shortening in lifelong trained male football players compared to age-matched inactive controls

    Progress in cardiovascular diseases

Telomerase activity

upin humans1

1 study
  1. Football training is linked with higher telomerase activity in humans (young football players vs young inactive controls) (4.2-fold).

    “YF had higher telomerase activity (4.2-fold, p = 0.001)”

    Humansyoung football players vs young inactive controlsmononuclear cellsmales

    Reduced telomere shortening in lifelong trained male football players compared to age-matched inactive controls

    Progress in cardiovascular diseases

More on Telomerase activity

Telomerase activity, TRF2, Ku70 and POT1a expression

no changein humans1

1 study
  1. Football training was not clearly linked with telomerase activity, TRF2, Ku70 and POT1a expression in humans (elderly football players vs age-matched inactive controls).

    “No significant between-group differences (p > 0.050) were observed in telomerase activity or anti-senescent factors (TRF2, Ku70 and POT1a) for EF vs EC.”

    Humanselderly football players vs age-matched inactive controlsmononuclear cellslifelongmales

    Reduced telomere shortening in lifelong trained male football players compared to age-matched inactive controls

    Progress in cardiovascular diseases

More on Telomerase activity, TRF2, Ku70 and POT1a expression

Rate of force development

upin humans1

1 study
  1. Football training increases rate of force development in humans (+89% RFD, +18% hamstring strength).

    “football training mainly resulted in enhanced hamstring strength (18 %, P < 0.05) and RFD (89 %, P < 0.0001)”

    Human trialskeletal muscle12 monthsmalesn = 9

    Positive effects of 1-year football and strength training on mechanical muscle function and functional capacity in elderly men

    European journal of applied physiology

Chair rising performance

upin humans1

1 study
  1. Football training improves chair rising performance in humans (+32% chair-rising performance, −24% stair-ascent time).

    “24 and 18 % reduced stair-ascent time, and 32 and 21 % increased chair-rising performance in FT and ST, respectively”

    Human trial12 monthsmalesn = 9

    Positive effects of 1-year football and strength training on mechanical muscle function and functional capacity in elderly men

    European journal of applied physiology

All 16

What is football training linked with?

1

Studies link football training with body weight.

Body weight

downin humans1

1 study
  1. Football training is associated with body weight in humans (78.2 ± 6.5 vs 91.2 ± 11.2 kg).

    “These findings were associated with a healthier body composition in trained than in untrained men [body weight: 78.2 ± 6.5 vs 91.2 ± 11.2 kg”

    Humansmales

    Effect of lifelong football training on the expression of muscle molecular markers involved in healthy longevity

    European journal of applied physiology

Latest