Engineered microalgae

1 paper2 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Labs are independent when their papers share no last author and no institution.

Against: findings that point the other way from most findings on the same outcome.

On aging: the drug’s trials ARN judged to be about aging, of every trial that tests it for any use.

No results posted: trials that ended more than a year ago with no results on ClinicalTrials.gov and no paper in ARN’s record.

Company ties: findings with an author at a company, or from a paper whose competing-interests statement declares ties to one.

1 lab in 1 country

Funders: China Postdoctoral Science Foundation and 3 more

Animals1

Outcomes

Intervertebral disc degeneration

downin rats1

1 study

Engineered microalgae decreases intervertebral disc degeneration in rats.
“In vivo, local injection of the engineered microalgae delays needle puncture-induced IDD in rats.”
Animalsneedle puncture-induced IDDlocal injection
Engineered microalgae-driven gel platform promotes the repairing of senescence-associated intervertebral disc degeneration in rats and goats
Journal of controlled release : official journal of the Controlled Release Society3 Dec 2025

More on Intervertebral disc degeneration

Cellular senescence

downin cells1

1 study

Engineered microalgae decreases cellular senescence in cells.
“In vitro, the engineered microalgae effectively scavenge intracellular ROS, stabilize mitochondrial membrane potential, reduce inflammatory cytokine secretion, and consequently alleviate NPC senescence while restoring extracellular matrix (ECM) homeostasis.”
Cellsin vitronucleus pulposus cell
Engineered microalgae-driven gel platform promotes the repairing of senescence-associated intervertebral disc degeneration in rats and goats
Journal of controlled release : official journal of the Controlled Release Society3 Dec 2025

Latest

1 in 12 months

Journal of Controlled Release6 Dec