Dodecamethylcyclohexasiloxane

Intervention

1 paper3 findings

PubChemChEBI

  • 1 lab in 1 country
  • Funders: National Key Research and Development Program of China and 1 more
  • Model organisms1

Outcomes

3

Oxidative stress and ROS signalling

upin worms1

1 study
  1. Dodecamethylcyclohexasiloxane induces oxidative stress and ROS signalling in worms.

    “At elevated concentrations, D6 induced oxidative stress and cellular damage”

    Model organismsat elevated concentrations (within 0.05-1.00 mg/L)

    Investigating the biphasic impacts of dodecamethylcyclohexasiloxane on Caenorhabditis elegans: From reproductive and mitochondrial dysfunctions to biochemical and molecular responses

    Environmental pollution (Barking, Essex : 1987)3 Jun 2025

More on Oxidative stress and ROS signalling

Growth

upin worms1

1 study
  1. Dodecamethylcyclohexasiloxane improves growth in worms.

    “low concentrations of D6 slightly enhanced growth and stimulated physiological responses”

    Model organismslow concentrations (within 0.05-1.00 mg/L)

    Investigating the biphasic impacts of dodecamethylcyclohexasiloxane on Caenorhabditis elegans: From reproductive and mitochondrial dysfunctions to biochemical and molecular responses

    Environmental pollution (Barking, Essex : 1987)3 Jun 2025

Lifespan

downin worms1

1 study
  1. Dodecamethylcyclohexasiloxane shortens lifespan in worms.

    “while higher concentrations significantly reduced growth and lifespan, indicating toxicity of D6.”

    Model organismshigher concentrations (within 0.05-1.00 mg/L)

    Investigating the biphasic impacts of dodecamethylcyclohexasiloxane on Caenorhabditis elegans: From reproductive and mitochondrial dysfunctions to biochemical and molecular responses

    Environmental pollution (Barking, Essex : 1987)3 Jun 2025

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