Dibutyl phthalate

1 paper1 finding

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Labs are independent when their papers share no last author and no institution.

Against: findings that point the other way from most findings on the same outcome.

On aging: the drug’s trials ARN judged to be about aging, of every trial that tests it for any use.

No results posted: trials that ended more than a year ago with no results on ClinicalTrials.gov and no paper in ARN’s record.

Company ties: findings with an author at a company, or from a paper whose competing-interests statement declares ties to one.

1 lab in 1 country

Funder: National Natural Science Foundation of China

Animals1

Outcomes

Femoral bone microarchitecture

downin mice1

1 study

Dibutyl phthalate impairs femoral bone microarchitecture in mice.
“prenatal DBP exposure induced dose-dependent deterioration in the male offspring's femoral bone microarchitecture, as revealed by micro-CT.”
Animalsprenatal exposuregavagefemoral bonemales
Maternal dibutyl benzene-1,2-dicarboxylate exposure accelerates bone marrow mesenchymal stem cells senescence to induce skeletal retardation in male offspring mice
Toxicology letters29 Jan 2026