Papers on dasatinib + quercetin

391 papers7 new in 30 days

Saturday, January 3

GSA 2025 AbstractJan 3

Clinical Trials of Senolytics in Alzheimer’s Disease Treatment and Prevention

Non-randomized trial in 12 peopleSenolytics

Paper

Wednesday, December 31

Nature CommunicationsDec 31

Chemotherapy-induced adipo-lineage cell senescence drives bone loss

Experiments in animalsChemotherapy

Paper

Tuesday, December 30

Aging CellDec 30

Senolytic Treatment With Dasatinib and Quercetin Reshapes Influenza-Specific CD8 T Cell Responses During Infection in Aged, Vaccinated Mice

Experiments in miceSenolytics

Paper

Friday, December 26

Cellular SignallingDec 26

The anti-aging drug Senolytics alleviates vascular endothelial cell senescence by antagonizing the JPX-BRD4-p65 complex

Experiments in animalsSenolytics

Paper

Wednesday, December 24

AAIC 2025 AbstractDec 24

Head‐to‐head comparison of two senolytic therapies in a mouse model of tauopathy

Experiments in miceSenolytics

Paper

AAIC 2025 AbstractDec 24

Senolytic treatment with Quercetin and Dasatinib mitigates decline in cardiac function and links heart remodeling to cognitive performance in adult Dahl Salt‐Sensitive Female Rats

Experiments in 13 ratsDasatinib

Paper

Tuesday, December 23

Aging CellDec 23

Senescent Cells Involved in Deterioration of Bone Microstructure by High-Frequency Parathyroid Hormone 1-34 Administration and Bone Loss

Experiments in miceBone loss

Paper

AAIC 2025 AbstractDec 23

The Dual Role of Tau in Neuroprotection and Disease: Neuronal Senescence as a Therapeutic Target

Trial in peopleInterventions

Paper

Monday, December 22

Annals of NeurologyDec 22

Senescent Cell Clearance Ameliorates Temporal Lobe Epilepsy and Associated Spatial Memory Deficits in Mice

Experiments in miceEpilepsy

Paper

Wednesday, December 17

Nature CommunicationsDec 17

GSDME-dependent pyroptosis drives abdominal aortic aneurysm via promoting vascular senescence

Experiments in micePyroptosis

Paper

Monday, December 1

Military Medical ResearchDec 1

β-catenin initiates peritoneal fibrosis by triggering mitochondrial fission-mediated mesothelial cell senescence fate transition

Study in peopleInterventions

Paper

Friday, November 28

Stem Cell Research & TherapyNov 28

Senescent bone marrow mesenchymal stem cells exacerbate subchondral bone sclerosis and osteoarthritis via the senescence-associated secretory phenotype

Experiments in miceOsteoarthritis

Paper

Thursday, November 27

International Journal of Molecular SciencesNov 27

Senolytic Treatment Improves Responsiveness to Mechanical Loading in the Skeleton of Aged Mice

Experiments in miceSenolytics

Paper

Wednesday, November 26

Aging and DiseaseNov 26

Long-term Senolytic Treatment Prevents Endothelial Dysfunction in Arterial Aging

Experiments in miceSenolytics

Paper

Monday, November 24

Frontiers in Cardiovascular MedicineNov 24

Frailty and cardiovascular disease: a bidirectional relationship with clinical implications

ReviewMechanisms

Paper

Monday, November 3

AHA Scientific Sessions 2025 AbstractNov 3

Intestinal Microbiota-derived Phenylacetic acid Accelerates Perivascular Adipose Tissue Senescence and Atherosclerosis in Aging

Experiments in miceCellular senescence

Paper

Thursday, October 23

Frontiers in ImmunologyOct 23

Targeting senescent microglia in progressive multiple sclerosis: a geroscience-informed approach

Experiments in miceMultiple sclerosis

Paper

Friday, October 17

The American Journal of Sports MedicineOct 17

Senolytic Combination of Dasatinib and Quercetin Promotes Tendon-to-Bone Healing by Mitigating Age-Related Senescence in Rats

Experiments in 12 ratsSenolytics

Paper

Thursday, October 16

Cell Biochemistry and FunctionOct 16

Dissecting Spatiotemporal Heterogeneity of Senescence Markers p16/p21 Across Tissues During Type 2 Diabetes Progression

Experiments in miceType 2 diabetes

Paper

Wednesday, October 15

Circulation ResearchOct 15

Vascular Niches Are the Primary Hotspots in Cardiac Aging

Experiments in miceInterventions

Paper

Saturday, October 11

InflammopharmacologyOct 11

Targeting the senescence-associated secretory phenotype to modify osteoarthritis in aging

ReviewOsteoarthritis

Paper

Monday, September 22

Journal of Alzheimer's DiseaseSep 22

Advancing Alzheimer's disease treatment: A literature review on senolytic intervention

ReviewSenolytics

Paper

Friday, September 19

Frontiers in MicrobiologySep 19

Dasatinib and Quercetin alleviate type 2 diabetic osteoporosis by regulating serum metabolite and gut microbiome

Experiments in miceDasatinib + quercetin

Paper

Tuesday, September 2

Particle and Fibre ToxicologySep 2

Neurometabolomic impacts of wood smoke and protective benefits of anti-aging therapeutics in aged female C57BL/6J mice

Experiments in miceInterventions

Paper

Friday, August 8

Fundamental ResearchAug 8

Targeted delivery of liposomal senolytics to alleviate cellular senescence-induced bone loss

Experiments in miceSenolytics

Paper

Friday, August 1

Cardiology in ReviewAug 1

Telomere Dynamics in Cardiovascular Aging: From Molecular Mechanisms to Precision Medicine

ReviewTelomerase and telomere maintenance

Paper

Tuesday, July 29

BiomedicinesJul 29

Targeting Cellular Senescence: Pathophysiology in Multisystem Age-Related Diseases

ReviewCellular senescence

Paper

Monday, July 28

PlacentaJul 28

Investigating the abnormalities and potential therapeutic targets in umbilical cord mesenchymal stem cells from preeclampsia

Study in peoplePreeclampsia

Paper

Alzheimer's Research & TherapyJul 28

A human neuron alzheimer's disease model reveals barriers to senolytic translatability

Experiments in human cellsSenolytics

Paper

Biochemical and Biophysical Research CommunicationsJul 28

Engineered bifunctional extracellular vesicles simultaneously promoting senolysis and efferocytosis for anti-aging therapy in diabetic mice

Experiments in miceExtracellular vesicles

Paper