InterventionsAnimals13 rats6 months

Senolytic treatment with Quercetin and Dasatinib mitigates decline in cardiac function and links heart remodeling to cognitive performance in adult Dahl Salt‐Sensitive Female Rats

AAIC 2025 Abstract

Abstract

Background: Cardiovascular risk factors, including elevated blood pressure (BP) and central arterial stiffness (CAS), an early vascular aging (EVA) characteristic, are associated with cognitive decline and dementia. In adult Dahl salt‐sensitive (DSS) rats, consuming a normal salt (NS; 0.

The paper

Santos CRD, Barnett MJ, McDevitt RA et al.

AAIC 2025 Abstract · 24 Dec 2025 · CC BY

Presented at AAIC 2025

doi.org/10.1002/alz70855_104317