Clinical & Experimental Ophthalmology
Novel Insight of Posterior Capsule Opacification: The Role of Lens Epithelial Cell Senescence
Experiments in rabbitsInterventions
Papers on dasatinib + quercetin
391 papers7 new in 30 days
Tuesday, July 15
Saturday, July 12
npj Aging
Nothobranchius furzeri: a vertebrate model for studying cardiac aging and cellular senescence
Experiments in killifishInterventions
Monday, July 7
Acta Biomaterialia
Human heart-on-a-chip model emulates structural and functional characteristics of diastolic dysfunction and reveals a beneficial role for senolytics
Experiments in human cellsSenolytics
Saturday, July 5
Cancer Cell
Chemotherapy awakens dormant cancer cells in lung by inducing neutrophil extracellular traps
Experiments in animalsLung
Tuesday, July 1
Research Square
Dasatinib and quercetin senolytic treatment delays early onset intervertebral disc degeneration in SM/J mice
Preprint: experiments in miceSenolytics
Friday, June 27
Thursday, June 19
Cellular and Molecular Neurobiology
Senolytic Treatment Attenuates Global Ischemic Brain Injury and Enhances Cognitive Recovery by Targeting Mitochondria
Experiments in miceSenolytics
Friday, June 13
ADA Scientific Sessions 2025 Abstract
Senolysis in Pancreatic β-Cells Improves Islet Transplantation Outcomes in Preclinical Models of Diabetes Mellitus
Experiments in miceType 1 diabetes
Tuesday, June 10
Monday, June 9
Osteoarthritis and Cartilage Open
Fibrocartilage repair involves chronic cellular senescence in a rat model of bone marrow stimulation
Experiments in ratsBones and joints
Saturday, June 7
International Immunopharmacology
Treatment with senolytic drugs ameliorates steroid-induced osteonecrosis of the femoral head by inhibiting osteoclastogenesis
Experiments in miceSenolytics
Tuesday, May 20
Scientific Reports
The adverse effects of chemotherapy on bone mass are not prevented by senolytics
Experiments in miceSenolytics
Tuesday, May 13
Frontiers in Medicine
Senolytic therapy reduces inflammation in epithelial cells from COPD patients and in smoke-exposure mice
Experiments in miceSenolytics
Friday, April 25
Science Advances
Single-cell morphology encodes functional subtypes of senescence in aging human dermal fibroblasts
Study in peopleBiomarkers
Neurotherapeutics
Evaluation of exploratory fluid biomarkers from a phase 1 senolytic trial in mild Alzheimer's disease
Non-randomized trial in 5 peopleSenolytics
bioRxiv
Single-cell morphology encodes functional subtypes of senescence in aging human dermal fibroblasts
Preprint: study of 50 peopleInterventions
Wednesday, April 23
PNAS Nexus
Depletion of senescent cells improves surgery-induced neuroinflammation in aged mice
Experiments in miceInterventions
Monday, April 21
Phytomedicine
Senolytic treatment alleviates cochlear senescence and delays age-related hearing loss in C57BL/6J mice
Experiments in miceSenolytics
Saturday, April 19
The Journal of Nutritional Biochemistry
Cardioprotective effect of senotherapy in chronically obese middle-aged female rats may be mediated by a MERCSs/Nrf2 interaction
Experiments in ratsInterventions
Friday, April 18
Cellular and Molecular Life Sciences
Nano-encapsulated senolytic cocktail attenuates germ cell senescence in female mice
Experiments in miceSenolytics
Saturday, April 12
Stem Cell Reviews and Reports
Attenuation of Cellular Senescence and Improvement of Osteogenic Differentiation Capacity of Human Liver Stem Cells Using Specific Senomorphic and Senolytic Agents
Experiments in human cellsSenolytics
Tuesday, April 8
Journal of Neuroinflammation
Senescent cell reduction does not improve recovery in mice under experimental autoimmune encephalomyelitis (EAE) induced demyelination
Experiments in miceInterventions
Tuesday, April 1
Research Square
Neurometabolomic impacts of wood smoke and protective benefits of anti-aging therapeutics in aged female C57BL/6J mice
Preprint: experiments in miceInterventions
Wednesday, March 19
Preprint
Heterogeneity and Asynchrony of p16- and p21-related Aging in Type 2 Diabetic Mouse Tissues
Preprint: experiments in miceInterventions
Tuesday, March 18
Animal Cells and Systems
Combination of dasatinib and quercetin promotes osteogenic differentiation and stemness maintenance of hPDLSCs via YAP/TAZ
Experiments in human cellsDasatinib
Thursday, March 13
Aging Cell
Cellular Senescence Is a Central Driver of Cognitive Disparities in Aging
Experiments in miceInterventions
Friday, March 7
Oral Diseases
Dasatinib and Quercetin Mitigate Age-Related Alveolar Bone Inflammaging and Neutrophil Infiltration
Experiments in miceDasatinib + quercetin
Thursday, February 27
EBioMedicine
A pilot study of senolytics to improve cognition and mobility in older adults at risk for Alzheimer's disease
Non-randomized trial in 12 peopleSenolytics