Benidipine

1. Benidipine inhibits inflammation in mice.

   “antihypertensive drugs (benidipine, nifedipine, verapamil, diltiazem) and anticholesterol drugs (lovastatin, simvastatin, pravastatin) strongly suppressed the leukocyte Kv1.3 channels and thus exerted anti-inflammatory effects”

   Reviewcortical interstitium

   Pathological and functional significance of aging mouse kidneys: clinical implications to reduce the risk of hyper- or hypokalemia in the elderly

   Kidney research and clinical practice·Aug 7, 2024

More on Inflammation

1. Benidipine inhibits KCNA3 in mice.

   “antihypertensive drugs (benidipine, nifedipine, verapamil, diltiazem) and anticholesterol drugs (lovastatin, simvastatin, pravastatin) strongly suppressed the leukocyte Kv1.3 channels”

   Reviewcortical interstitium

   Pathological and functional significance of aging mouse kidneys: clinical implications to reduce the risk of hyper- or hypokalemia in the elderly

   Kidney research and clinical practice·Aug 7, 2024

More on KCNA3

1. Benidipine protects against pulmonary emphysema in mice.

   “Benidipine, decreased senescent lung cells and ameliorates lung emphysema in a mouse model.”

   Animalsin a mouse model of cigarette smoke-induced lung emphysemalung

   Benidipine calcium channel blocker promotes the death of cigarette smoke-induced senescent cells and improves lung emphysema

   Aging·Dec 12, 2023

More on Pulmonary emphysema

1. Benidipine decreases cellular senescence in mice.

   “Benidipine, decreased senescent lung cells and ameliorates lung emphysema in a mouse model.”

   Animalsin a mouse model of cigarette smoke-induced lung emphysemalung

   Benidipine calcium channel blocker promotes the death of cigarette smoke-induced senescent cells and improves lung emphysema

   Aging·Dec 12, 2023

More on Cellular senescence