Nifedipine

3 papers

1 trial, none about aging

Humans1
Animals1

Trial sponsors

Medicare Hospital
1 trialPhase 484 people

Latest

3 in 12 months

The Journal of PhysiologyFeb 25

An age-associated decline in the role of the sarcoplasmic reticulum and associated calcium-handling proteins sets the pace for sinoatrial node function

Experiments in animalsEndoplasmic reticulum

AAIC 2025 AbstractDec 26

Sildenafil is a candidate drug for Alzheimer’s disease: Mechanism‐of‐action observation in patient iPSC‐derived brain organoids and a 5xFAD mouse model

Cohort study in peopleAlzheimer's disease

Experimental PhysiologyNov 17

Role of S1P- and Rho-kinase signalling in age-related myogenic tone deficiency in murine resistance arteries

Experiments in miceMechanisms

Kidney Research and Clinical PracticeAug 7

Pathological and functional significance of aging mouse kidneys: clinical implications to reduce the risk of hyper- or hypokalemia in the elderly

ReviewKidney

European Journal of PharmacologyJul 23

Downregulation of stromal interaction molecule-1 is implicated in the age-associated vasoconstriction dysfunction of aorta, intrarenal, and coronary arteries

Experiments in miceMechanisms

BiomedicinesDec 24

How Do Young and Old Spontaneously Hypertensive Rats Respond to Antihypertensive Therapy? Comparative Studies on the Effects of Combined Captopril and Nifedipine Treatment

Experiments in ratsInterventions

Journal of Physiology and BiochemistryApr 9

Aging modifies receptor expression but not muscular contractile response to angiotensin II in rat jejunum

Experiments in animalsMechanisms

Aging CellOct 5

Dopamine D4 receptor activation restores CA1 LTP in hippocampal slices from aged mice

Experiments in cellsMechanisms

Journal of GerontologyJan 1

Influence of aging on the alpha 1-receptor-mediated glycogenolysis in rat hepatocytes

Experiments in rat cellsMechanisms