Aminoguanidine

2 papers2 findings

1 lab in 1 country

Funder: National Science and Technology Council

Animals1

Outcomes

2

IGFBP3

downin mice1

1 study

Aminoguanidine decreases IGFBP3 in mice.
“AGE accumulation and IGFBP-3 expression were reciprocally attenuated by both interventions”
Animalsin naturally aged micekidneymales
Functional interaction between advanced glycation end-products and IGFBP-3 contributes to renal pathology in aging-associated chronic kidney disease
Tissue & cell15 May 2026

Renal dysfunction

downin mice1

1 study

Aminoguanidine decreases renal dysfunction in mice.
“Pharmacological inhibition of AGE formation or IGFBP-3 neutralization significantly ameliorated these age-associated impairments.”
Animalsin naturally aged micekidneymales
Functional interaction between advanced glycation end-products and IGFBP-3 contributes to renal pathology in aging-associated chronic kidney disease
Tissue & cell15 May 2026

Latest

2 in 12 months

Tissue & Cell20 May

Functional interaction between advanced glycation end-products and IGFBP-3 contributes to renal pathology in aging-associated chronic kidney disease

Experiments in miceChronic kidney disease

ChemRxiv26 Apr

The Canalised Cleavage of Glucosepane

Preprint: experiments in cellsInterventions

Advances in Gerontology1 Jan

H2S as an activator of the NO-sGC signaling pathway in dilation of cerebral vessels: changes in aging

Experiments in ratsMechanisms

Biogerontology24 Jun

Calorie restriction mimetics against aging and inflammation

ReviewInterventions

Life Sciences17 Aug

Role of advanced glycation end-products in age-associated kidney dysfunction in naturally aging mice

Experiments in animalsMechanisms