Cellular senescence
downin animals1
ALPHA-CYANO-4-HYDROXYCINNAMIC acid decreases cellular senescence.
“targeting lactate transport with the MCT inhibitor CHC significantly ameliorated disease progression and senescence in CIA”
Animalscollagen-induced arthritis
Lactate worsened arthritis and bone erosion in animals
NPJ aging14 Oct 2026
Rheumatoid arthritis progression
downin animals1
ALPHA-CYANO-4-HYDROXYCINNAMIC acid decreases rheumatoid arthritis progression.
“targeting lactate transport with the MCT inhibitor CHC significantly ameliorated disease progression and senescence in CIA”
Animalscollagen-induced arthritis
Lactate worsened arthritis and bone erosion in animals
NPJ aging14 Oct 2026
In animals with induced arthritis, blocking lactate transport reduced disease progression more effectively than blocking the body's own lactate production.In animals with induced arthritis, blocking lactate transport reduced disease progression more effectively than blocking the body's own lactate production.