Aldehydes

  • Animals1

Outcomes

1

Premature aging

upin reviews1

1 study
  1. Aldehydes induce premature aging.

    “The accumulation of these substances can lead to the cross-linking of intracellular DNA and proteins, thereby disrupting cellular function and contributing to the processes of premature aging”

    Review

    From aldehyde metabolism to delay aging: targeting ALDH2 as a novel strategy

    Free radical biology & medicine9 May 2025

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Journal of the American Heart Association

Genetic analysis links shared DNA signals to artery disease

An observational analysis of human genetic study results identified 289 lead DNA variants across 177 risk regions and prioritised candidate protein targets.An observational analysis of human genetic study results identified 289 lead DNA variants across 177 risk regions and prioritised candidate protein targets.

Genetic association study of participants in human artery disease genetic studiesMechanisms

Limit: The genetic signals concern a modelled ASCVD common factor rather than directly measured disease