Aav-centenarian SIRT6

Intervention

1 paper1 finding

  • 1 lab in 1 country
  • Funders: Fondation pour la Recherche Médicale and 2 more
  • Cells1

Outcomes

1

Genome instability

downin human cells1

1 study
  1. Aav-centenarian SIRT6 decreases genome instability in human cells.

    “AAV)-mediated delivery of centenarian SIRT6 or pharmacological activation of SIRT6 using fucoidan from Fucus vesiculosus (Fucoidan-FV) partially attenuated aging-associated molecular defects”

    Cellsin progeria fibroblasts

    Centenarian SIRT6 variants elevate SIRT6 protein and enhance cellular senescence resistance

    Research square19 Jun 2026Preprint

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