LINE1 derepression

Biomarker

1 paper1 finding

  • Cells1

Interventions

1

Fucoidan

downin human cells1

1 study
  1. Fucoidan decreases LINE1 derepression in human cells.

    “pharmacological activation of SIRT6 using fucoidan from Fucus vesiculosus (Fucoidan-FV) partially attenuated aging-associated molecular defects, including genome instability and LINE1 derepression”

    Cellsin progeria fibroblasts

    Centenarian SIRT6 variants elevate SIRT6 protein and enhance cellular senescence resistance

    Research square19 Jun 2026Preprint

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