LINE1 derepression
1 paper1 finding
- Cells1
Interventions
1Fucoidan
downin human cells1
1 study
Fucoidan
downin human cells1
Fucoidan decreases LINE1 derepression in human cells.
“pharmacological activation of SIRT6 using fucoidan from Fucus vesiculosus (Fucoidan-FV) partially attenuated aging-associated molecular defects, including genome instability and LINE1 derepression”
Cellsin progeria fibroblasts
Centenarian SIRT6 variants elevate SIRT6 protein and enhance cellular senescence resistance
Research square19 Jun 2026Preprint
Latest
1 in 12 monthsResearch Square
Centenarian SIRT6 variants elevate SIRT6 protein and enhance cellular senescence resistance
Preprint: experiments in human cellsCellular senescence
Cell Metabolism
LINE1 Derepression in Aged Wild-Type and SIRT6-Deficient Mice Drives Inflammation
Experiments in miceSIRT6