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4-hydroxybenzyl alcohol

Intervention

2 papers4 findings

C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

  • 1 lab in 1 country
  • Funders: National Institutes of Health and 2 more
  • Model organisms1

Outcomes

3

Survival rate under stress

upin worms1

1 study

  1. 4-hydroxybenzyl alcohol increases survival rate under stress in worms.

    “HBA improved the survival rate of worms under stresses of oxidation, heat, and pathogenic bacteria.”

    Model organisms

    Para-Hydroxybenzyl Alcohol Delays the Progression of Neurodegenerative Diseases in Models of Caenorhabditis elegans through Activating Multiple Cellular Protective Pathways

    Oxidative medicine and cellular longevityMar 31, 2022

Physical function

upin worms1

1 study

  1. 4-hydroxybenzyl alcohol improves physical function in worms.

    “significantly improve the age-related physiological functions of worms.”

    Model organisms

    Para-Hydroxybenzyl Alcohol Delays the Progression of Neurodegenerative Diseases in Models of Caenorhabditis elegans through Activating Multiple Cellular Protective Pathways

    Oxidative medicine and cellular longevityMar 31, 2022

Lifespan

upin worms1

1 study

  1. 4-hydroxybenzyl alcohol extends lifespan in worms (> 25%).

    “HBA could increase the average lifespan of N2 worms by more than 25%”

    Model organisms

    Para-Hydroxybenzyl Alcohol Delays the Progression of Neurodegenerative Diseases in Models of Caenorhabditis elegans through Activating Multiple Cellular Protective Pathways

    Oxidative medicine and cellular longevityMar 31, 2022

Associations

1

Neurodegenerative disease

downin worms1

1 study

  1. 4-hydroxybenzyl alcohol lowers the risk of neurodegenerative disease in worms.

    “HBA effectively delayed the progression of neurodegenerative diseases, such as Alzheimer's disease, Parkinson's disease, and Huntington's disease in models of C. elegans.”

    Model organisms

    Para-Hydroxybenzyl Alcohol Delays the Progression of Neurodegenerative Diseases in Models of Caenorhabditis elegans through Activating Multiple Cellular Protective Pathways

    Oxidative medicine and cellular longevityMar 31, 2022

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