C, W, M, H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.
Labs are independent when their papers share no last author and no institution.
No results posted: trials that ended over a year ago with no results on ClinicalTrials.gov and no paper reporting them.
Includes the processes named after it and trials of drugs aimed at it.
9 independent labs in 8 countries
17 trials, 6 with no results posted
Funders: Gouvernement du Canada | Canadian Institutes of Health Research and others
10 of 17 trials sponsored by developers of drugs aimed at it
Human trial1
Humans5
Animals13
Cells3
In silico3
Latest
14 papers in 12 months
International Journal of Innovative Technologies in Social Science·
A selective protein inhibitor reduced disease severity in two experimental models of colitis, a form of intestinal inflammation.A selective protein inhibitor reduced disease severity in two experimental models of colitis, a form of intestinal inflammation.
Compared with no biologic exposure, adjusted osteoporosis hazard ratios—a measure of relative risk—were 0.83 for tumor necrosis factor inhibitors and 0.19 for…Compared with no biologic exposure, adjusted osteoporosis hazard ratios—a measure of relative risk—were 0.83 for tumor necrosis factor inhibitors and 0.19 for interleukin-17 inhibitors.