TNF

There are 26 papers on TNF in aging research: 1 trial and 5 observational studies in people, 13 in animals, 3 in cells, 1 review. The newest story, Nov 2, 2026: “Protein-blocking drug eased intestinal inflammation in mice”.

Gene

26 papers study it

HGNCNCBI GeneTaxon

4 new papers in 30 daysSee all 26

None of its findings points the other way.

  • 9 independent labs in 8 countries
  • 17 trials, 6 with no results posted
  • Funders: Gouvernement du Canada | Canadian Institutes of Health Research and others
  • 10 of 17 trials sponsored by developers of drugs aimed at it
  • Human trial1
  • Humans5
  • Animals13
  • Cells3
  • In silico3

Latest

Dec 2025: 0Jan 2026: 0Feb 2026: 9Mar 2026: 2Apr 2026: 0May 2026: 0Jun 2026: 1Jul 2026: 0Aug 2026: 0Sep 2026: 0Oct 2026: 1Nov 2026: 114 papers in 12 months
The Journal of Rheumatology

Arthritis drugs may be linked to lower osteoporosis risk

Compared with no biologic exposure, adjusted osteoporosis hazard ratios—a measure of relative risk—were 0.83 for tumor necrosis factor inhibitors and 0.19 for…Compared with no biologic exposure, adjusted osteoporosis hazard ratios—a measure of relative risk—were 0.83 for tumor necrosis factor inhibitors and 0.19 for interleukin-17 inhibitors.

Cohort study of 37,708 peopleOsteoporosis

See all 26