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Cellular senescenceSenescent cells, the SASP, and the drugs that clear or quiet them.
Aging clocksEpigenetic, blood-based and other measures of biological age.
mTOR & rapamycinNutrient sensing through mTOR, and the rapalogs that dial it down.
Partial reprogrammingYamanaka factors, epigenetic reprogramming and cellular rejuvenation.
NAD+ & sirtuinsNAD+ precursors, sirtuins and the metabolism of aging cells.
MitochondriaMitochondrial function, mitophagy and energy decline with age.
Dietary restrictionCaloric restriction, fasting and time-restricted eating.
GLP-1 drugsSemaglutide, tirzepatide and what incretin drugs do to aging.
InflammagingChronic low-grade inflammation and the aging immune system.
Brain agingCognitive aging, neurodegeneration and the aging brain.

TFEB

GeneHomo sapiens1 paperHGNC 11753NCBI Gene 7942Taxon 9606

In silico1

Latest

2

Exploring the Neuroprotective Effects of Walnut (Juglans regia L.) Against Cognitive Impairment in Alzheimer's Disease Through the MAPK-mTORC1-TFEB-Mediated Endolysosomal Pathway: A Network Pharmacology and Molecular Docking Approach

In silicoInternational Journal of Molecular Sciences

·28 Sep

Autophagy in sarcopenic obesity: muscle-adipose crosstalk, metabolic regulation, and exercise-based interventions

ReviewMetabolism

·26 Sep

Related

Autophagy2
Disabled macroautophagy2
Loss of proteostasis2
ABCA11
AMPK signalling1
Alzheimer's disease1
Chronic inflammation1
FOXO signalling1
Lipid and ceramide metabolism1
MAPK/ERK signalling1
Mitochondrial dysfunction1
Mitophagy1
Sirtuin signalling1
Beta-amyloid1
Gallic acid1
Insulin resistance1

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