SEPP1

1 paper1 finding

HGNC NCBI Gene Taxon

1 lab in 1 country

Funders: National Key Research and Development Program of China and 1 more

Animals1

Effects

1

Cellular senescence

downin mice1

1 study

SEPP1 decreases cellular senescence in mice.
“Sepp1 is a key regulator of neutrophil senescence-associated reprogramming and immune suppression in HCC through selenium-dependent epigenetic remodelling.”
Animalsin hepatocellular carcinoma mouse models
Selenoprotein P deficiency drives hepatocellular carcinoma progression via induction of neutrophil senescence and immunosuppressive microenvironment
Gut1 Apr 2026

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Gut2 Apr

Selenoprotein P deficiency drives hepatocellular carcinoma progression via induction of neutrophil senescence and immunosuppressive microenvironment

Experiments in miceHepatocellular carcinoma