GOT1

Gene1 paper2 findingsHGNC 4432NCBI Gene 2805Taxon 9606

C · W · M · H: cells, worms or flies, mice, humans. Dark: independent labs found the same change there. Light: one lab or one study. Outline: nothing yet.

Labs are independent when their papers share no last author and no institution.

Against: findings that point the other way from most findings on the same outcome.

No results posted: trials that ended more than a year ago with no results on ClinicalTrials.gov and no paper in ARN’s record.

Company ties: findings with an author at a company, or from a paper that declares the maker’s interest.

A gene’s or a process’s line counts the gene with the processes named after it, as NLRP3 with the NLRP3 inflammasome, and the trials of drugs aimed at it.

1 lab in 1 country

Funder: National Natural Science Foundation of China

  • Cells1

Effects

2

Oxidative stress and ROS signalling

downin human cells1

1 study
  1. GOT1 decreases oxidative stress and ROS signalling in human cells.

    Cellsco-condensation with ME1 in acidic conditionslung cell

    A pH-Responsive fluorescence lifetime probe reveals GOT1 phase separation in cellular anti-senescence · Smart molecules : open access · 3 Sep 2026

Oxidative stress and ROS signalling →

Cellular senescence

downin human cells1

1 study
  1. GOT1 decreases cellular senescence in human cells.

    Cellsvia liquid-liquid phase separationlung cell

    A pH-Responsive fluorescence lifetime probe reveals GOT1 phase separation in cellular anti-senescence · Smart molecules : open access · 3 Sep 2026

Cellular senescence →

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