TERF2IP
- 1 lab in 1 country
- Funders: Department of Biotechnology, Ministry of Science and Technology, India and 1 more
- Humans1
- Cells1
Effects
1Cellular senescence
upin cells1
1 study
Cellular senescence
upin cells1
TERF2IP increases cellular senescence in cells.
“Knockdown of either TERF2IP or TRF2 impaired intermittent hyperglycemia-induced p53 and p21 expression and associated endothelial senescence.”
CellsIntermittent hyperglycemia; shown by TERF2IP knockdownendothelial cell
International journal of biological macromolecules4 Jun 2025
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International Journal of Biological Macromolecules
Regulation of shelterin proteins TERF2IP and TRF2 by the MLL2-H3K4me3-p65 axis drives hyperglycemia-dependent endothelial senescence
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