TERF2IP

  • 1 lab in 1 country
  • Funders: Department of Biotechnology, Ministry of Science and Technology, India and 1 more
  • Humans1
  • Cells1

Effects

1

Cellular senescence

upin cells1

1 study
  1. TERF2IP increases cellular senescence in cells.

    “Knockdown of either TERF2IP or TRF2 impaired intermittent hyperglycemia-induced p53 and p21 expression and associated endothelial senescence.”

    CellsIntermittent hyperglycemia; shown by TERF2IP knockdownendothelial cell

    Regulation of shelterin proteins TERF2IP and TRF2 by the MLL2-H3K4me3-p65 axis drives hyperglycemia-dependent endothelial senescence

    International journal of biological macromolecules4 Jun 2025

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