PBX3

1 paper2 findings

HGNC NCBI Gene Taxon

1 lab in 1 country

Funder: Natural Science Foundation of Jiangxi Province

Animals1

Effects

2

Allergic rhinitis

upin mice1

1 study

PBX3 increases allergic rhinitis in mice.
“PBX3 knockdown significantly alleviated AR symptoms in mice, including reduced sneezing, nose rubbing, nasal discharge”
Animalsshown by knockdown
PBX3 regulates mast cell parthanatos via TOP2A mediated DNA damage in allergic rhinitis
iScience20 Mar 2026

More on Allergic rhinitis

TOP2A

upin mouse cells1

1 study

PBX3 increases TOP2A in mouse cells.
“PBX3 directly binds to the TOP2A promoter to regulate transcription”
Cellsin vitro
PBX3 regulates mast cell parthanatos via TOP2A mediated DNA damage in allergic rhinitis
iScience20 Mar 2026

Latest

1 in 12 months

iScience20 Apr

PBX3 regulates mast cell parthanatos via TOP2A mediated DNA damage in allergic rhinitis

Experiments in miceDNA damage response