FASEB Journal
Protein loss in vessel-lining cells increased plaque area in mice
Mice lacking Matrin-3 in vessel-lining cells had a 1.41-fold increase in artery plaque area compared with mice without the deficiency.Mice lacking Matrin-3 in vessel-lining cells had a 1.41-fold increase in artery plaque area compared with mice without the deficiency.
Mouse studyMechanisms
Who was studiedLDL receptor-knockout mice, against mice without endothelial Matrin-3 deletion
What changedMice lacking endothelial Matrin-3 had a 1.41-fold increase in whole-aorta plaque area compared with control mice
The catchLocal vessel effects and liver-driven lipid changes were not separated experimentally