There are 3 papers on kin-10 in aging research: none in people yet, 3 in animals.
At a glance
The findings reach worms or flies, none yet in people. 1 lab in 1 country.
None of its findings points the other way.
- 1 lab in 1 country
- Funders: Ministry of Science ICT and Future Planning and 4 more
- Model organisms3
Effects
3LGG-1 expression
upin worms1
1 study
LGG-1 expression
upin worms1
kin-10 increases LGG-1 expression in worms (shown by kin-10 knockdown in nematodes).
“in the expression of lgg-1 (the Caenorhabditis elegans ortholog of LC3B), bec-1 (the C. elegans ortholog of beclin-1), and unc-51 (the C. elegans ortholog of Ulk1), mediated by kin-10”
Model organismsshown by kin-10 knockdown in nematodes
Protein Kinase CK2 Is Upregulated by Calorie Restriction and Induces Autophagy
Molecules and cells
Locomotion
downin worms1
1 study
Locomotion
downin worms1
kin-10 impairs locomotion in worms (shown by knockdown).
“Knockdown of kin-10 (the ortholog of CK2β) led to a short lifespan phenotype and induced age-related biomarkers, including retardation of locomotion”
Model organismsshown by knockdown
Downregulation of protein kinase CK2 activity induces age-related biomarkers in C. elegans
Oncotarget
Lifespan
downin worms1
1 study
Lifespan
downin worms1
kin-10 shortens lifespan in worms (shown by knockdown).
“Knockdown of kin-10 (the ortholog of CK2β) led to a short lifespan phenotype”
Model organismsshown by knockdown
Downregulation of protein kinase CK2 activity induces age-related biomarkers in C. elegans
Oncotarget