There are 2 papers on LGG-1 expression in aging research: none in people yet, 2 in animals.
2 papers study it4 findings
See all 2 papers on LGG-1 expression
- Model organisms2
Interventions
1Resveratrol
upin worms1
1 study
Resveratrol
upin worms1
Resveratrol increases LGG-1 expression in kin-10 knockdown nematodes.
“The treatment with the AKT inhibitor triciribine, the AMPK activator AICAR, or the SIRT1 activator resveratrol rescued a reduction”
Model organismsin kin-10 knockdown nematodes
Protein Kinase CK2 Is Upregulated by Calorie Restriction and Induces Autophagy
Molecules and cells
Upstream
3kin-10
upin worms1
1 study
kin-10
upin worms1
kin-10 increases LGG-1 expression in worms (shown by kin-10 knockdown in nematodes).
“in the expression of lgg-1 (the Caenorhabditis elegans ortholog of LC3B), bec-1 (the C. elegans ortholog of beclin-1), and unc-51 (the C. elegans ortholog of Ulk1), mediated by kin-10”
Model organismsshown by kin-10 knockdown in nematodes
Protein Kinase CK2 Is Upregulated by Calorie Restriction and Induces Autophagy
Molecules and cells
hlh-30
upin worms1
1 study
hlh-30
upin worms1
hlh-30 increases LGG-1 expression in worms (shown by RNA interference knockdown).
“and the expression of autophagy gene lgg-1 decreased”
Model organismsshown by RNA interference knockdown
Autophagy Plays a Role in the Prolongation of the Life Span of Caenorhabditis elegans by Astaxanthin
Rejuvenation research
daf-16
upin worms1
1 study
daf-16
upin worms1
daf-16 increases LGG-1 expression in worms (shown by RNA interference knockdown).
“and the expression of autophagy gene lgg-1 decreased”
Model organismsshown by RNA interference knockdown
Autophagy Plays a Role in the Prolongation of the Life Span of Caenorhabditis elegans by Astaxanthin
Rejuvenation research