Deep learning
Method29 papers
- Humans8
- Cells1
- In silico19
Latest
28RaiLED-AD: Rationale-Guided Knowledge Transfer for Alzheimer's Disease Prediction from Electronic Health Records
Wearable movement data links to hundreds of human diseases
In 70,473 adults followed for up to 10 years, 210 wearable activity phenotypes were linked to 406 diseases, with step intensity and circadian rhythm…In 70,473 adults followed for up to 10 years, 210 wearable activity phenotypes were linked to 406 diseases, with step intensity and circadian rhythm showing prominent ties.
Speech model flags cognitive decline and generates explanations
Tested across six dataset and task conditions, the bilingual framework outperformed three baselines while directly generating natural-language…Tested across six dataset and task conditions, the bilingual framework outperformed three baselines while directly generating natural-language explanations for clinicians.
Disentangling and Fusing Neurostructural and Vascular Ageing for Retinal Age Prediction
Brain signatures of BMI detect systemic disease better than BMI
Across six human cohorts and a 2.3-year follow-up, neural networks identified brain structural patterns tied to cardiometabolic and pulmonary…Across six human cohorts and a 2.3-year follow-up, neural networks identified brain structural patterns tied to cardiometabolic and pulmonary conditions.
Facial foundation model estimates clinical biomarkers
Pretrained on 10 million images, the model assessed 62 biomarkers across eight physiological systems, reaching a median Pearson's r of 0.172 across…Pretrained on 10 million images, the model assessed 62 biomarkers across eight physiological systems, reaching a median Pearson's r of 0.172 across four cohorts.
Deep learning matches experts in scoring aortic valve calcium
Algorithm scores correlated strongly with expert assessments at r = 0.99, identifying moderate-to-severe aortic stenosis with 0.92 sensitivity and…Algorithm scores correlated strongly with expert assessments at r = 0.99, identifying moderate-to-severe aortic stenosis with 0.92 sensitivity and 0.98 specificity.
Simple anatomical features match complex AI models on brain MRIs
Across about 80,000 human participants, simple anatomical measurements performed as well as complex AI models while improved pretraining boosted…Across about 80,000 human participants, simple anatomical measurements performed as well as complex AI models while improved pretraining boosted biological age estimation.
Automated tool counts teeth from routine brain MRI
The model counted teeth with a mean absolute error of 1.96 and matched manual associations with cognitive scores in a 233-person cohort.The model counted teeth with a mean absolute error of 1.96 and matched manual associations with cognitive scores in a 233-person cohort.
Repeat-consistency learning for improving repeatability of brain-age prediction from structural MRI
Interpretable hybrid deep learning features of pectoralis on low-dose chest CT for detecting type 2 diabetes
Model infers spatial neighborhoods in dissociated single cells
The computational tool predicted cellular proximity across brain regions and identified age-associated neighborhood remodeling in an 8-month Alzheimer…The computational tool predicted cellular proximity across brain regions and identified age-associated neighborhood remodeling in an 8-month Alzheimer dataset.
DECIPHER decodes cell types and predicts age from bulk omics
Tested across multiple molecular platforms, the framework separates technical variation from biological signal to infer cell proportions and…Tested across multiple molecular platforms, the framework separates technical variation from biological signal to infer cell proportions and chronological age across independent human cohorts.
AI lung scan score links to fibrosis progression and mortality
A baseline deep learning score above 0.5 was associated with a 13.41% relative annual fibrosis increase and higher mortality in two human cohorts.A baseline deep learning score above 0.5 was associated with a 13.41% relative annual fibrosis increase and higher mortality in two human cohorts.