Journal of the American Society of Nephrology
Telomere Dysfunction in Renal Tubular Epithelial Cells Leads to Kidney Fibrosis
Experiments in miceTelomerase and telomere maintenance
Papers on tubular injury
80 papers9 new in 30 days
Tuesday, July 8
Thursday, June 26
Tuesday, June 24
Frontiers in Endocrinology
ER-α36 prevents high glucose-induced cellular senescence and apoptosis in renal tubular cell
Experiments in human cellsApoptosis
Wednesday, May 7
American Journal of Physiology Renal Physiology
Altered renal vascular patterning reduces ischemic kidney injury and limits age-associated vascular loss
Experiments in miceKidney
Friday, March 28
The Journal of Experimental Medicine
Breast cancer gene-1 (BRCA1) potentiates maladaptive repair after kidney injury
Experiments in miceBRCA1
Thursday, February 13
American Journal of Nephrology
DOT1L Regulates Cellular Senescence during the Progression from Acute Kidney Injury to Chronic Kidney Disease via the microRNA-222-5p/WNT9B Signaling Pathway
Experiments in animalsWnt/β-catenin signaling
Wednesday, January 22
Friday, January 3
American Journal of Nephrology
A New Model of Chronic Kidney Disease, Metabolic Derangements, and Heart Failure with Preserved Ejection Fraction in Aging Swine
Experiments in pigsKidney
Monday, November 18
bioRxiv
Altered renal vascular patterning reduces ischemic kidney injury and limits vascular loss associated with aging
Preprint: experiments in miceKidney
European Journal of Pharmacology
Empagliflozin attenuates renal tubular ferroptosis in preeclampsia via tazarotene-induced gene 1
Experiments in miceEmpagliflozin
Thursday, July 4
American Journal of Physiology Renal Physiology
NAD deficiency contributes to progressive kidney disease in HIV-nephropathy mice
Experiments in miceKidney
Thursday, June 27
Pharmaceutics
Targeted Drug Therapy for Senescent Cells Alleviates Unilateral Ureteral Obstruction-Induced Renal Injury in Rats
Experiments in ratsKidney
Saturday, May 18
European Journal of Pharmaceutics and Biopharmaceutics
Engineered urolithin A-laden functional polymer-lipid hybrid nanoparticles prevent cisplatin-induced proximal tubular injury in vitro
Experiments in human cellsUrolithin A
Wednesday, April 3
Friday, February 23
Clinical Science
Intervention treatment reducing cellular senescence inhibits tubulointerstitial fibrosis in diabetic mice following acute kidney injury
Experiments in 12 miceKidney
Tuesday, January 2
Sichuan Da Xue Xue Bao Yi Xue Ban
Research Progress in Stress-Induced Senescence of Renal Tubular Cells in Diabetic Nephropathy
ReviewCellular senescence
Thursday, November 30
American Journal of Physiology Renal Physiology
SGLT2 inhibitor dapagliflozin protects the kidney in a murine model of Balkan nephropathy
Experiments in miceSGLT2 inhibitors
Thursday, November 2
Kidney Medicine
Structured Moderate Exercise and Biomarkers of Kidney Health in Sedentary Older Adults: The Lifestyle Interventions and Independence for Elders Randomized Clinical Trial
Randomized trial in 1,381 peopleExercise
Monday, September 11
Acta Pharmacologica Sinica
Fisetin ameliorates fibrotic kidney disease in mice via inhibiting ACSL4-mediated tubular ferroptosis
Experiments in miceFisetin
Monday, August 21
Frontiers in Endocrinology
Tubular injury in diabetic kidney disease: molecular mechanisms and potential therapeutic perspectives
ReviewKidney
Monday, May 15
Aging Cell
PTEN-induced kinase 1 is associated with renal aging, via the cGAS-STING pathway
Experiments in micecGAS–STING signaling
Tuesday, April 4
Research Square
Urinary Sirtuin2/Creatinine Ratio Correlates with Severity of Albuminuria and Tubular Injury in Type 2 Diabetes Patients
Preprint: cross-sectional study in peopleAlbuminuria
Thursday, December 1
Signal Transduction and Targeted Therapy
FFAR4 improves the senescence of tubular epithelial cells by AMPK/SirT3 signaling in acute kidney injury
Experiments in miceAMPK signaling
Saturday, November 12
Thursday, October 20
Friday, April 8
Oxidative Medicine and Cellular Longevity
Cigarette Smoke Exposure Increases Glucose-6-phosphate Dehydrogenase, Autophagy, Fibrosis, and Senescence in Kidney Cells In Vitro and In Vivo
Experiments in miceAutophagy
Sunday, March 27
European Journal of Pharmacology
Effects of losartan on bladder dysfunction due to aging-related severe hypertension in rats
Experiments in ratsHypertension
Thursday, March 24
Journal of Tissue Engineering and Regenerative Medicine
Selective kidney targeting increases the efficacy of mesenchymal stromal/stem cells for alleviation of murine stenotic-kidney senescence and damage
Experiments in miceKidney
Tuesday, February 8
Naunyn-Schmiedeberg's Archives of Pharmacology
Fisetin attenuates renal ischemia/reperfusion injury by improving mitochondrial quality, reducing apoptosis and oxidative stress
Experiments in ratsFisetin