Skeletal muscle dysfunction

Loss of the lipid enzyme PNPLA7 impairs skeletal muscle and mitochondria in mice

Researchers identified PNPLA7 as an essential regulator of phosphatidylcholine catabolism necessary for maintaining mouse muscle fiber size and endurance.Researchers identified PNPLA7 as an essential regulator of phosphatidylcholine catabolism necessary for maintaining mouse muscle fiber size and endurance.