Metabolic dysregulation

Disease

2 papers

  • Animals1

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BMC Geriatrics

Frailty and a metabolic measure linked to risk of death

An observational study of 2,573 UK and 803 Chinese older adults with atrial fibrillation and no diabetes linked combined metabolic and frailty assessments to differing…An observational study of 2,573 UK and 803 Chinese older adults with atrial fibrillation and no diabetes linked combined metabolic and frailty assessments to differing death risks.

Cohort study of 2,573 peopleBiomarkers
bioRxiv

Boosting sugar breakdown increased bone mass in aged mice

Experiments linked reduced bone formation to impaired sugar breakdown, while genetic changes that enhanced the process improved bone-forming cell function in aged mice.Experiments linked reduced bone formation to impaired sugar breakdown, while genetic changes that enhanced the process improved bone-forming cell function in aged mice.

Preprint: experiments in miceBones and joints
GeroScience

Biological aging and frailty linked to thinner central retinas

Blood metabolic profiles statistically accounted for 81.14% of the link with one biological age measure, compared with 19.92% for another and 32.27% for frailty.Blood metabolic profiles statistically accounted for 81.14% of the link with one biological age measure, compared with 19.92% for another and 32.27% for frailty.

Cohort study of 45,542 peoplePopulations