Kidney cancer

1. lifestyle-based risk prediction model predicts kidney cancer in humans (C-statistic 0.68).

   Humans10.9 yearsn = 265,712

   Development and Internal Validation of a Lifestyle-Based Risk Prediction Model for 10-Year Incident Kidney Cancer in the 45 and Up Study · Research Square · 28 Sep 2026 · Preprint

1. Diabetes raises the risk of kidney cancer in humans.

   Humans10.9 yearsn = 265,712

   Development and Internal Validation of a Lifestyle-Based Risk Prediction Model for 10-Year Incident Kidney Cancer in the 45 and Up Study · Research Square · 28 Sep 2026 · Preprint

Diabetes →

1. Hypertension raises the risk of kidney cancer in humans.

   Humans10.9 yearsn = 265,712

   Development and Internal Validation of a Lifestyle-Based Risk Prediction Model for 10-Year Incident Kidney Cancer in the 45 and Up Study · Research Square · 28 Sep 2026 · Preprint

Hypertension →

1. Obesity raises the risk of kidney cancer in humans.

   Humans10.9 yearsn = 265,712

   Development and Internal Validation of a Lifestyle-Based Risk Prediction Model for 10-Year Incident Kidney Cancer in the 45 and Up Study · Research Square · 28 Sep 2026 · Preprint

Obesity →

1. Exercise lowers the risk of kidney cancer in humans.

   Humans10.9 yearsn = 265,712

   Development and Internal Validation of a Lifestyle-Based Risk Prediction Model for 10-Year Incident Kidney Cancer in the 45 and Up Study · Research Square · 28 Sep 2026 · Preprint

Exercise →

1. HLA-A raises the risk of kidney cancer in humans (RERI = 3.24, 95%CI=1.20-5.28).

   Humansin womenfemales

   Independent and joint effects of lifestyle, human leukocyte antigen polymorphisms on cancer risk: findings from the UK Biobank · Frontiers in immunology · 11 Sep 2026

HLA-A →