Glioblastoma multiforme
4 papers2 findings
- Model organisms1
- Cells2
Interventions
1Caloric restriction
downin silico1
1 study
Caloric restriction
downin silico1
Caloric restriction decreases glioblastoma multiforme in silico.
“DR can mitigate the onset and development of GBM via the gene CA3”
In silicovia the gene CA3
Scientific reports28 May 2025
Upstream
1CA3
downin silico1
1 study
CA3
downin silico1
CA3 decreases glioblastoma multiforme in silico.
“modulating CA3 expression can effectively curb the genesis and progression of GBM.”
In silicomodulating CA3 expression
Scientific reports28 May 2025
Trial sponsors
Novartis Pharmaceuticals Corporation
Company2 trialsPhase 3281 people
Company1 trialPhase 340 people
Company1 trialPhase 39 people
Company1 trialPhase 250 people
Company1 trialPhase 1/2160 people
Company1 trialPhase 1/230 people
Company1 trialPhase 1/220 people
Company1 trialPhase 1/24 people
Latest
1 in 12 monthsJournal of Cellular and Molecular Medicine
The GPCR Connection: Linking Alzheimer's Disease and Glioblastoma
ReviewMechanisms
Scientific Reports
CA3 bridges dietary restriction to glioblastoma suppression and tumor progression as a key downstream effector
Experiments in cellsMechanisms
Scientific Reports
The compartment-specific manipulation of the NAD⁺/NADH ratio affects the metabolome and the function of glioblastoma
Experiments in cellsMechanisms
International Journal of Molecular Sciences
Repurposed Drugs Celecoxib and Fmoc-L-Leucine Alone and in Combination as Temozolomide-Resistant Antiglioma Agents-Comparative Studies on Normal and Immortalized Cell Lines, and on C. elegans
Experiments in wormsInterventions
Biochemistry and Biophysics Reports
5-ALA localises to the autophagy compartment and increases its fluorescence upon autophagy enhancement through caloric restriction and spermidine treatment in human glioblastoma
Experiments in human cellsDietary restriction
International Journal of Molecular Sciences
Identification of CDK1, PBK, and CHEK1 as an Oncogenic Signature in Glioblastoma: A Bioinformatics Approach to Repurpose Dapagliflozin as a Therapeutic Agent
Computational studyInterventions
Research Square
Inhibition of TRF1 can accelerate aging and induce autophagy through the P53-SIRT6 pathway in glioblastoma multiforme
Preprint: experiments in cellsMechanisms
Medical Oncology
Exploring the inverse association of glioblastoma multiforme and Alzheimer's disease via bioinformatics analysis
Computational studyMechanisms
Current Medicinal Chemistry
The Potential Therapeutic Impact of Metformin in Glioblastoma Multiforme
ReviewInterventions