Demyelinating disease

2 papers

Animals1

Trial sponsors

Indapta Therapeutics
Company1 trialPhase 134 people

Latest

5 in 12 months

Acta Neurologica Belgica6 Oct

Shorter Leukocyte telomere length as a marker of biological aging in relapsing-remitting multiple sclerosis

Cross-sectional study in peopleTelomere length

Research Square7 Aug

Shorter Leukocyte Telomere Length as a Marker of Biological Aging in Relapsing-Remitting Multiple Sclerosis

Preprint: case-control study in peopleTelomere length

Nature Aging5 Mar

ACSS2 maintains oligodendrocyte progenitor cell pool and is required for myelination during development and aging

Experiments in miceInterventions

Brain Sciences28 Jan

Targeting Lifestyle in CNS Inflammatory Demyelinating Diseases: Insights from Diet and Exercise as Potential Disease Modifiers

ReviewInterventions

GSA 2025 Abstract3 Jan

Polygenic Nature of Cortical Aging Reveals Cytoskeletal Regulation as a Core Pathway of Resilience

Genetic association study of 41,708 peopleMechanisms

International Journal of Molecular Sciences13 Sep

Dynamic Intercellular Networks in the CNS: Mechanisms of Crosstalk from Homeostasis to Neurodegeneration

ReviewCellular homeostasis

Nature Communications1 Sep

Metformin alters mitochondria-related metabolism and enhances human oligodendrocyte function

Study in peopleMetformin

Nature Neuroscience12 Sep

DOR activation in mature oligodendrocytes regulates α-ketoglutarate metabolism leading to enhanced remyelination in aged mice

Experiments in miceLipid and ceramide metabolism

Cell Stem Cell3 Oct

Metformin Restores CNS Remyelination Capacity by Rejuvenating Aged Stem Cells

Experiments in rodentsMetformin