Cholestatic liver injury
3 papers study it7 more mention it
- Humans1
Funding
1 grant since 2018National Institute of Diabetes and Digestive and Kidney DiseasesUS$713.4k
Latest
1 paper in 12 monthsJournal of Advanced Research
Conjugated bile acids facilitate cholangiocyte senescence to promote cholestatic liver diseases via STING signaling
Experiments in micecGAS–STING signaling
Free Radical Biology & Medicine
Mitochondrial dysfunction-mediated hepatocyte senescence is involved in cholestatic liver injury
Study in peopleInterventions
Frontiers in Molecular Biosciences
Biliary Epithelial Senescence in Liver Disease: There Will Be SASP
Free Radical Biology & Medicine
Paricalcitol inhibits oxidative stress-induced cell senescence of the bile duct epithelium dependent on modulating Sirt1 pathway in cholestatic mice
Experiments in animalsInterventions
Laboratory Investigation; a Journal of Technical Methods and Pathology
Knockout of α-calcitonin gene-related peptide attenuates cholestatic liver injury by differentially regulating cellular senescence of hepatic stellate cells and cholangiocytes
Experiments in animalsMechanisms
The American Journal of Pathology
The Secretin/Secretin Receptor Axis Modulates Ductular Reaction and Liver Fibrosis through Changes in Transforming Growth Factor-β1-Mediated Biliary Senescence
Experiments in animalsMechanisms
Hepatology
Forkhead box A2 regulates biliary heterogeneity and senescence during cholestatic liver injury in mice‡
Experiments in animalsInterventions