Chemotherapy induced peripheral neuropathy
1 paper1 finding
- Animals1
Interventions
1Senolytics
downin animals1
1 study
Senolytics
downin animals1
Senolytics protect against chemotherapy induced peripheral neuropathy.
“Genetic or pharmacological ablation of senescent fibroblasts prevents neuropathy and reverses established disease”
Animalschemotherapy
Senescent peripheral fibroblasts initiate chemotherapy-induced peripheral neuropathy
bioRxiv5 Aug 2026Preprint
Trial sponsors
Company1 trialPhase 464 people
Company1 trialPhase 2/360 people
Seoul National University Hospital
1 trialPhase 368 people
2 trialsPhase 253 people
Academic and Community Cancer Research United
1 trialPhase 288 people
1 trialPhase 280 people
1 trialPhase 268 people
1 trialPhase 262 people
Funding
1 grant since 2025National Institute on AgingUS$589.1k
Latest
1 in 12 monthsbioRxiv
Senescent peripheral fibroblasts initiate chemotherapy-induced peripheral neuropathy
Preprint: experiments in animalsCellular senescence