Ganciclovir
- 1 lab in 1 country
- Funders: National Cancer Institute and 2 more
- Animals1
Outcomes
2Intervertebral disc degeneration
downin mice1
1 study
Intervertebral disc degeneration
downin mice1
Ganciclovir decreases intervertebral disc degeneration in mice.
“Systemic clearance of p16INK4a -positive senescent cells mitigates age-associated intervertebral disc degeneration”
Animalsp16-3MR transgenic miceintervertebral disc
Aging cell21 Mar 2019
Proteoglycan matrix content
upin mice1
1 study
Proteoglycan matrix content
upin mice1
Ganciclovir increases proteoglycan matrix content in mice.
“increased overall proteoglycan matrix content along with improved histological disc features”
Animalsp16-3MR mice treated with ganciclovirintervertebral disc
Aging cell21 Mar 2019