Hpv vaccination

Intervention3 papers6 findings

  • Humans1

Outcomes

4

Herd protection

upin humans1

1 study
  1. Hpv vaccination increases herd protection in humans.

    Reviewin community-randomised trials

    Elimination of HPV-associated cancers: universal HPV vaccination and the role of anal screening - a meeting report · BMC proceedings · 22 Sep 2026

Abnormal cytology

downin humans1Very low certainty

1 study
  1. Hpv vaccination decreases abnormal cytology in humans (-13.4% (PR = 0.866, 95% CI 0.841–0.894)).

    Humanscohort eligible for adolescent vaccination vs 2019 unvaccinated cohortfemales

    Twelve Years Later: How Vaccination Changed the Cervical Cancer Landscape in Brazil · Research Square · 24 Aug 2026 · Preprint

Cervical precancerous lesions

downin humans1

1 study
  1. Hpv vaccination decreases cervical precancerous lesions in humans.

    Reviewin vaccinated populations

    The need to change cervical cancer screening in the post-human papillomavirus vaccination era: the interplay between disease prevalence and risk, test characteristics, and efficiency of screening programs · Journal of the National Cancer Institute. Monographs · 1 Aug 2026

Cervical precancerous lesions →

Positive predictive value of screening

downin humans1

1 study
  1. Hpv vaccination decreases positive predictive value of screening in humans.

    Reviewin vaccinated populations

    The need to change cervical cancer screening in the post-human papillomavirus vaccination era: the interplay between disease prevalence and risk, test characteristics, and efficiency of screening programs · Journal of the National Cancer Institute. Monographs · 1 Aug 2026

Positive predictive value of screening →

Associations

2

Cervical intraepithelial neoplasia grade 2+

downin humans1Very low certainty

1 study
  1. Hpv vaccination lowers the risk of cervical intraepithelial neoplasia grade 2+ in humans.

    Humanscohort eligible for adolescent vaccination vs 2019 unvaccinated cohortfemales

    Twelve Years Later: How Vaccination Changed the Cervical Cancer Landscape in Brazil · Research Square · 24 Aug 2026 · Preprint

Cervical intraepithelial neoplasia grade 2+ →

Cervical cancer

downin humans1−96% nationallyVery low certainty

1 study
  1. Hpv vaccination lowers the risk of cervical cancer in humans (-96% nationally).

    Humanscohort eligible for adolescent vaccination vs 2019 unvaccinated cohortfemales

    Twelve Years Later: How Vaccination Changed the Cervical Cancer Landscape in Brazil · Research Square · 24 Aug 2026 · Preprint

Cervical cancer →

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