Age-related skeletal muscle degeneration

There are 2 papers on age-related skeletal muscle degeneration in aging research: none in people yet, 2 in animals. The newest story, Oct 30, 2026: “Fat buildup linked to declining leg power in older adults”.

Disease

2 papers study it3 more mention it2 findings

See all 5

  • Animals1
  • Model organisms1

Interventions

1

Endurance exercise

downin flies1

1 study
  1. Endurance exercise protects against age-related skeletal muscle degeneration in flies (on a high-salt diet).

    “it protected the myofibrillar fibers and mitochondria of skeletal muscle in Drosophila on a high-salt diet”

    Model organismson a high-salt dietskeletal muscle

    Muscular TOR knockdown and endurance exercise ameliorate high salt and age-related skeletal muscle degradation by activating the MTOR-mediated pathway

    PloS one

More on Endurance exercise

Upstream

1

Tor

mediatesin flies1

1 study
  1. Tor mediates age-related skeletal muscle degeneration in flies.

    “the muscle TOR gene plays an important role in endurance exercise against HSD-induced age-related skeletal muscle degeneration”

    Model organismsrequired for the protective effect of endurance exercise against high-salt-diet-induced degenerationskeletal muscle

    Muscular TOR knockdown and endurance exercise ameliorate high salt and age-related skeletal muscle degradation by activating the MTOR-mediated pathway

    PloS one

More on Tor

Latest

Dec 2025: 0Jan 2026: 0Feb 2026: 0Mar 2026: 0Apr 2026: 0May 2026: 0Jun 2026: 0Jul 2026: 1Aug 2026: 0Sep 2026: 1Oct 2026: 0Nov 2026: 02 papers in 12 months
Archives of Gerontology and Geriatrics

Fat buildup linked to declining leg power in older adults

MRI scans of 70 older adults over three years linked coordinated fat buildup across muscles, rather than muscle shrinkage alone, to declining leg power.MRI scans of 70 older adults over three years linked coordinated fat buildup across muscles, rather than muscle shrinkage alone, to declining leg power.

Cohort · 70 peoplePopulations