Tubular senescence
3 papers study it35 more mention it
- Animals3
Funding
1 grant since 2020National Institute of Diabetes and Digestive and Kidney DiseasesUS$451.8k
Latest
15 papers in 12 monthsInternational Immunopharmacology
Remodeling lipid and mitochondrial homeostasis: a novel mechanism by which polydatin attenuates renal tubular senescence in chronic kidney disease
Experiments in miceChronic kidney disease
Biochimica et Biophysica Acta Molecular Basis of Disease
Pannexin1 promotes cellular senescence by triggering mtDNA release to activate the cGAS-STING pathway
Experiments in micecGAS–STING signaling
FASEB Journal
SGLT2 Inhibition Attenuates Renal Tubular Senescence by Suppressing CTRP1-Mediated Glucotoxic Stress in Diabetic Kidney Disease
Case-control study in peopleSGLT2 inhibitors
Renal Failure
AMD1-mediated polyamine metabolism governs tubular repair fate by restraining senescence after kidney injury
Experiments in miceKidney
Acta Pharmacologica Sinica
CYFIP2 deficiency ameliorates renal interstitial fibrosis through attenuating tubular senescence in hypertensive nephropathy
Experiments in miceCellular senescence
Biochemical Pharmacology
SGLT2i-Triggered hyperglycosuria Unveils CDKN2A-Driven distal tubular senescence and EMT, Fueling renal fibrosis
Experiments in miceSGLT2 inhibitors