Thrombospondin-1
- Humans4
- Animals3
Funding
3 grants since 2018National Institute on AgingUS$2.4mNational Heart, Lung, and Blood InstituteUS$2.3mAmerican Heart AssociationUS$300k
Rejuvenation of aged hematopoietic stem cells and endothelial niches by thrombospondin-1 blockade
National Institute on AgingUniversity of FloridaUS$217.5k2022–2024
Progressive degenerative role of Nox and thrombospondin-1 in the aging vasculature
National Heart, Lung, and Blood InstituteUniversity of Pittsburgh at PittsburghUS$577.1k2019–2024
Progressive degenerative role of Nox and thrombospondin-1 in the aging vasculature
American Heart AssociationUniversity of PittsburghUS$300k2018–2019
Latest
14 papers in 12 monthsAntioxidants & Redox Signaling
Immune Checkpoint Inhibitor-Induced Cardiovascular Disease: The Role of Accelerated Senescence in Vascular Dysfunction
ReviewImmune response
Experimental & Molecular Medicine
N-terminal thrombospondin-1 enhances muscle function and tissue-specific metabolic adaptation in response to exercise and cold exposure
Experiments in miceExercise
Reproductive Sciences
The KAT5-TSP-1 Axis Maintains Ovarian Redox Homeostasis and Is Impaired in Polycystic Ovary Syndrome
Experiments in ratsPolycystic ovary syndrome
BMC Pulmonary Medicine
Plasma proteomic profiling uncovers the age-related molecular changes in chronic obstructive pulmonary disease
Case-control study of 70 peopleChronic obstructive pulmonary disease
Cell Reports Medicine
Early-stage multi-cancer detection through a plasma extracellular vesicle protein signature
Cohort study of 764 peopleCancer
International Journal of Molecular Sciences
Thrombospondin 1-CD47 Signalling Modulates Vascular Smooth Muscle Cell Senescence in Chronic Kidney Disease
Experiments in miceCellular senescence
Aging Cell
Astrocyte Senescence Impairs Synaptogenesis due to Thrombospondin-1 Loss
Experiments in miceCellular senescence