iScience
Extra DNA-organizing protein makes the gut leakier in flies
In fruit fly experiments, excess DNA-organizing protein pushed gut stem cells into a nondividing state and led to cell death.In fruit fly experiments, excess DNA-organizing protein pushed gut stem cells into a nondividing state and led to cell death.
Fly studyGut and microbiome
Who was studiedAdult Drosophila flies, against GFP-expressing control flies
What changedGut leakage increased in 10-day-old flies overexpressing dCAPD3 compared with GFP-expressing controls
The catchGeneral stress from protein overexpression could explain the increased gut leakage