MCM7

2 papers1 finding

HGNC NCBI Gene Taxon

1 lab in 1 country

Humans1
Cells1

Effects

1

Cellular senescence

downin human cells1

1 study

MCM7 inhibits cellular senescence in human cells.
“MCM7 knockdown significantly inhibited HepG2 cell proliferation and upregulated senescence enforcers p16 and p21”
Cellsshown by knockdownliver
Machine learning-driven multi-omics integration uncovers a senescence associated molecular axis in HCC
Frontiers in immunology8 May 2026

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Chronic DNA Replication Stress Reduces Replicative Lifespan of Cells by TRP53-Dependent, microRNA-Assisted MCM2-7 Downregulation

Experiments in mouse cellsMechanisms